Huibin Chang designed and built a new type of additive textile manufacturing method to realize the high-throughput control alignment of micro/nanofibers in complex 3D geometries. His method can produce large-scale 3D scaffolds with controllable arrangement and orientation, which have been used in the first biological hybrid model to manufacture a human helical ventricular in antibacterial packaging to protect and extend the shelf-life of food.
His method demonstrates production rates comparable to the current industrial procedures while providing support for micro/nano length scales and controlled 3D alignments, proven to be a critical technology in industrial manufacturing.
For the first time, he uncovered how the heart allocates strain and achieves a large ejection fraction. By developing the helical ventricular platform, he made many discoveries and achievements in cardiac physiology, and he is the first one to demonstrate ventricular torsion in a vitro system, providing a clinic-relevant indicator for the predictive power of biomedical analysis.
He also showed creatively that the antibacterial fibers can be deposited directly on avocados to inhibit the proliferation of microorganisms on them and reduce their weight loss, thus extending their shelf life. This provides a potential method for the production of scalable, low-cost, and environment-friendly food packaging systems.