Photo of Dalong Ni

Biotechnology & medicine

Dalong Ni

Nanomaterial-based repair medicine, offering novel strategies to repair organ injuries.

Year Honored
2023

Organization
School of Medicine affiliated Ruijin Hospital, Shanghai Jiao Tong University

Region
Asia Pacific

Hails From
Asia Pacific

Organ injury, such as acute kidney injury, ischemic stroke, and osteoarthritis, often results in complications that can be life-threatening or even fatal. Recently, many nanomaterials have emerged as promising repair agents for various organ injuries.

Dalong Ni focuses on the field of nanomaterial-based repair medicine (abbreviated as “nanorepair medicine”), by synthesizing new nanostructures/nanozymes and synergetic strategies for repairing acute liver/kidney/lung injury, inflammatory bowel disease, osteoarthritis/osteoporosis, etc., and revealing their repairing mechanism in vivo.

Ni leads a group named “Nanorepair Medicine” Lab, which is a creative and cooperative research team, aiming to repair different acute or chronic organ injuries using nanotechnology as a tool. His lab provides some innovative strategies for organ injury repair: 

  1. scavenging reactive oxygen species directly to repair acute liver/kidney injury or chronic inflammatory bowel disease
  2. scavenging reactive oxygen species combined with gene therapy for repairing osteoarthritis
  3. regulating disease microenvironment with acid neutralization and immune regulation for osteoporosis reversion

Ni’s research provides valuable references for clinics since there is no effective methods/drugs for organ injury in clinics. Ni is working closely with doctors in Ruijing Hospital and pharmaceutical factory for translating medicine.